Tag Archives: frozen tissue samples

How To Process FFPE Tissue Blocks?

FPE tissue blocks are a great way to preserve tissue samples for future use. They can be used for research and for medical education. They are also useful tool for studying the effects of drugs or diseases on tissues. Processing FFPE tissue blocks can be a tricky process. If you also want to buy FFPE tissue block samples for research purposes, you can visit https://www.geneticistinc.com/blog/storing-ffpe-blocks.

 

What is Pathology?

 

Here are a few tips to help make the process easier:

1. Make Sure The Tissue Block Is Properly Frozen: Freezing the tissue block correctly will help to prevent damage during the processing steps. The optimal temperature range for freezing FFPE tissue blocks is between -20 and -40 degrees Celsius.

2. Minimize Processing Time: The longer the processing time is, the greater the chance that damage will occur to the tissue block. Processed FFPE tissue blocks should be stored in a dry environment and used as soon as possible.

3. Use Proper Equipment: Proper equipment will help to minimize damage during the processing steps. Equipment that is not suitable for processing FFPE tissue blocks may cause excessive heat or pressure which can damage the tissue block.

4. Follow Specific Instructions: Specific instructions for processing FFPE tissue blocks are provided with each kit. It is important to follow these instructions carefully to ensure successful results.

5. Have A Backup Plan: If steps in the processing process do not go as planned, have a backup plan ready in case of an error. This will help to minimize the amount of time needed to re-process the tissue block.

The above are a few ways to process FFPE tissue blocks. The most common way is to freeze the tissue block and then cut it into small pieces. This is the method that we use at the lab. Another way is to place the tissue block in a cryostat and then freeze it until it becomes a solid block. This is the method that is used in some research labs.